Dr. Pedro Zapater Hernández

Department: Desarrollo e Innovación en Biotecnología

Sanitaria de Elche (IDiBE). Immunopharmacology GROUP.

Phone: +34 965 913 868

Email: pzapater@umh.es

ResearchGate: Pedro Zapater

Current Position: Clinical Pharmacologist. Professor of Pharmacology. Department of Pharmacology, Paediatrics and Organic Chemistry, School of Medicine, Universidad Miguel Hernández        

Clinical Pharmacologist. Unit of Clinical Pharmacology. Hospital General Universitario de Alicante.

Research Fields

  • Nervous and immune regulation of inflammatory process.

  • Inflammation and stress in the pathogenesis of cancer.

  • Use of drugs in special populations: cirrhosis, pancreatitis, inflammatory bowel disease.

Representative Publications

  • Zapater P, Almenara S, Gutiérrez A, Sempere L, García M, Laveda R, Martínez A, Scharl M, Cameo JI, Linares R, González-Navajas JM, Wiest R, Rogler G, Francés R. Actual Anti-TNF Trough Levels Relate to Serum IL-10 in Drug-Responding Patients With Crohn's Disease. (2019) Inflammatory Bowel Diseases. Jul 17;25(8):1357-1366. doi: 10.1093/ibd/izz012.

  • Gimenez P, Garcia-Martinez I, Francés R, Gonzalez-Navajas JM, Mauri M, Alfayate R, Almenara S, Miralles C, Palazon JM, Carnicer F, Pascual S, Such J, Horga JF, Zapater P. Treatment with non-selective beta-blockers affects the systemic inflammatory response to bacterial DNA in patients with cirrhosis. (2018) Liver International. Dec;38(12):2219-2227. doi: 10.1111/liv.13890. Epub 2018 Jun 19.

  • Fuster-Lluch O, Zapater-Hernández P, Gerónimo-Pardo M. Pharmacokinetic Study of Intravenous Acetaminophen Administered to Critically Ill Multiple-Trauma Patients at the Usual Dosage and a New Proposal for Administration. The Journal of Clinical Pharmacology. octubre de 2017; 57(10):1345-52.

  • Zapater P, Llanos L, Barquero C, Bellot P, Pascual S, Carnicer F, et al. Acute Effects of Dipyrone on Renal Function in Patients with Cirrhosis: A Randomized Controlled Trial. Basic & Clinical Pharmacology & Toxicology. marzo de 2015;116(3):257-63.

  • Zapater P, Gómez-Hurtado I, Peiró G, González-Navajas JM, García I, Giménez P, et al. Beta-Adrenergic Receptor 1 Selective Antagonism Inhibits Norepinephrine-Mediated TNF-Alpha Downregulation in Experimental Liver Cirrhosis. Jacobs R, editor. PLoS ONE. 20 de agosto de 2012;7(8):e43371.

Company Agreements

  • Contracts and agreements of collaboration with companies for the study of inflammation and immune response in chronic pathologies such as osteoarthritis (BIOIBERICA)

Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche

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Av/ de la Universidad, s/n

03202 Elche, Alicante



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