Dr. Pedro Zapater Hernández

Department: Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE). Immunopharmacology GROUP.

Phone: +34 965 913 868

Email: pzapater@umh.es

ResearchGate: Pedro Zapater

Current Position: Clinical Pharmacologist. Professor of Pharmacology. Department of Pharmacology, Paediatrics and Organic Chemistry, School of Medicine, Universidad Miguel Hernández. Clinical Pharmacologist. Unit of Clinical Pharmacology. Hospital General Universitario de Alicante.

Research Fields

  • Nervous and immune regulation of inflammatory process.

  • Inflammation and stress in the pathogenesis of cancer.

  • Use of drugs in special populations: cirrhosis, pancreatitis, inflammatory bowel disease.

Representative Publications

  • Almenara S, Lozano B, Gimenez P, Herrera I, Miralles C, Bellot P, Rodríguez M, Francés R, Gonzalez-Navajas JM, Pascual S, Zapater P. Functionality of beta-adrenergic receptors in patients with cirrhosis treated chronically with non-selective beta-blockers. Hepatol Int. 2020 Sep;14(5):858-868. doi: 10.1007/s12072-020-10083-5.

  • Zapater P, Almenara S, Gutiérrez A, Sempere L, García M, Laveda R, Martínez A, Scharl M, Cameo JI, Linares R, González-Navajas JM, Wiest R, Rogler G, Francés R. Actual Anti-TNF Trough Levels Relate to Serum IL-10 in Drug-Responding Patients With Crohn's Disease. (2019) Inflammatory Bowel Diseases. Jul 17;25(8):1357-1366. doi: 10.1093/ibd/izz012.
     

  • Gimenez P, Garcia-Martinez I, Francés R, Gonzalez-Navajas JM, Mauri M, Alfayate R, Almenara S, Miralles C, Palazon JM, Carnicer F, Pascual S, Such J, Horga JF, Zapater P. Treatment with non-selective beta-blockers affects the systemic inflammatory response to bacterial DNA in patients with cirrhosis. (2018) Liver International. Dec;38(12):2219-2227. doi: 10.1111/liv.13890. Epub 2018 Jun 19.

  • Fuster-Lluch O, Zapater-Hernández P, Gerónimo-Pardo M. Pharmacokinetic Study of Intravenous Acetaminophen Administered to Critically Ill Multiple-Trauma Patients at the Usual Dosage and a New Proposal for Administration. The Journal of Clinical Pharmacology. Octubre de 2017; 57(10):1345-52.

  • Zapater P, Llanos L, Barquero C, Bellot P, Pascual S, Carnicer F, et al. Acute Effects of Dipyrone on Renal Function in Patients with Cirrhosis: A Randomized Controlled Trial. Basic & Clinical Pharmacology & Toxicology. marzo de 2015;116(3):257-63.

Company Agreements

  • Contracts and agreements of collaboration with companies for the study of inflammation and immune response in chronic pathologies such as osteoarthritis (BIOIBERICA)