Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche

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Av/ de la Universidad, s/n

03202 Elche, Alicante

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© 2017  Universidad Miguel Hernández. Diseño Web: C. Sala Ripoll 

Dr. Pedro Zapater Hernández

Department: Instituto de Bioingeniería. Unit of Pharmacology and Clinical Trials

Phone: +34 965 913 868

Email: pzapater@umh.es

ResearchGate: Pedro Zapater

Current Position: Clinical Pharmacologist. Professor of Pharmacology. Department of Pharmacology, Paediatrics and Organic Chemistry, School of Medicine, Universidad Miguel Hernández        

Clinical Pharmacologist. Unit of Clinical Pharmacology. Hospital General Universitario de Alicante.

Research Fields

  • Nervous and immune regulation of inflammatory process.

  • Inflammation and stress in the pathogenesis of cancer.

  • Use of drugs in special populations: cirrhosis, pancreatitis, inflammatory bowel disease.

Representative Publications

  • Piñero P, Juanola O, Caparrós E, Zapater P, Giménez P, González-Navajas JM, et al. Toll-like receptor polymorphisms compromise the inflammatory response against bacterial antigen translocation in cirrhosis. Scientific Reports. 18 de abril de 2017; 7:46425.

  • Fuster-Lluch O, Zapater-Hernández P, Gerónimo-Pardo M. Pharmacokinetic Study of Intravenous Acetaminophen Administered to Critically Ill Multiple-Trauma Patients at the Usual Dosage and a New Proposal for Administration. The Journal of Clinical Pharmacology. octubre de 2017; 57(10):1345-52.

  • Juanola O, Gómez-Hurtado I, Zapater P, Moratalla A, Caparrós E, Piñero P, et al. Selective intestinal decontamination with norfloxacin enhances a regulatory T cell-mediated inflammatory control mechanism in cirrhosis. Liver International. 23 de mayo de 2016;36(12):1811-20.

  • Zapater P, Llanos L, Barquero C, Bellot P, Pascual S, Carnicer F, et al. Acute Effects of Dipyrone on Renal Function in Patients with Cirrhosis: A Randomized Controlled Trial. Basic & Clinical Pharmacology & Toxicology. marzo de 2015;116(3):257-63.

  • Zapater P, Gómez-Hurtado I, Peiró G, González-Navajas JM, García I, Giménez P, et al. Beta-Adrenergic Receptor 1 Selective Antagonism Inhibits Norepinephrine-Mediated TNF-Alpha Downregulation in Experimental Liver Cirrhosis. Jacobs R, editor. PLoS ONE. 20 de agosto de 2012;7(8):e43371.

Company Agreements

  • Contracts and agreements of collaboration with companies for the study of inflammation and immune response in chronic pathologies such as osteoarthritis (BIOIBERICA)