Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche

logo IB_white.png

Av/ de la Universidad, s/n

03202 Elche, Alicante

Localización

¡Síguenos!

  • twitter_icon_white
  • blog_icon_white-01
  • youtube_icon_white

© 2017  Universidad Miguel Hernández. Diseño Web: C. Sala Ripoll 

Dr. María Rose Ponce Molet

Department: Instituto de Bioingeniería

Phone: +34 966 658 503

Email: mrponce@umh.es

Current Position: Professor of Genetics, Universidad Miguel Hernández.

Research Fields

One of the mechanisms regulating the expression of eukaryotic genes is mediated by small interfering RNAs (siRNAs), which include microRNAs (miRNAs). To negatively regulate their targets, siRNAs are incorporated into RNA-induced silencing complexes (RISCs), whose main component is a protein of the ARGONAUTE (AGO) family. The miRNA pathway has great biotechnological potential since through its manipulation any endogenous or viral gene can be silenced. We are studying the action and interactions of AGO1 in Arabidopsis thaliana.

Representative Publications

  • Jover-Gil, S., Paz-Ares, J., Micol, J.L., Ponce, M.R.Multi-gene silencing in Arabidopsis: a collection of artificial microRNAs targeting groups of paralogs encoding transcription factors. (2014) Plant Journal 80, 149-160.

  • Micol-Ponce, R., Aguilera, V., Ponce, M.R. A genetic screen for suppressors of a hypomorphic allele of Arabidopsis ARGONAUTE1. (2014) Scientific Reports 4, 5533.

  • Wilson-Sánchez, D., Rubio-Díaz, S., Muñoz-Viana, R., Pérez-Pérez, J.M., Jover-Gil, S., Ponce, M.R., Micol, J.L. Leaf phenomics: a systematic reverse genetic screen for Arabidopsis leaf mutants. (2014) Plant Journal 79, 878-891.

  • Fernández-Nohales, P., Domenech, M.J., Martínez de Alba, A.E., Micol, J.L., Ponce, M.R., Madueño, F. AGO1 controls arabidopsis inflorescence architecture possibly by regulating TFL1 expression. (2014) Annals of Botany 114, 1471-1481.