Department: Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE) /

Structure-Function Relationships in Membrane Proteins Group

Phone: +34 966 658 466

Email: 

Current Position: Associate Professor of Physical Chemistry, Universidad Miguel Hernandez.

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Research Fields

• Structure-function relationship in membrane proteins.

• Lipid-protein interactions.

• Modulation of ion channel structure and function.

Representative Publications

• Giudici AM, Díaz-García C, Renart ML, Counho A, Prieto M, González-Ros JM, Poveda JA. Tetraoctylammonium, a Long Chain Quaternary Ammonium Blocker, Promotes a Noncollapsed, Resng-Like Inacvated State in KcsA (2021). Int J Mol Sci. 6;22(2):490. doi: 10.3390/ijms22020490.

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• Renart ML, Giudici AM, Díaz-García C, Molina ML, Morales A, González-Ros JM, Poveda JA. Modulaon of Funcon, Structure and Clustering of K+ Channels by Lipids: Lessons Learnt from KcsA (2020). Int J Mol Sci. 21(7):2554. doi: 10.3390/ijms21072554.

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• Poveda JA, Giudici AM, Renart ML, Millet O, Morales A, González-Ros JM, Oakes V, Furini S, Domene C. Modulation of the potassium channel KcsA by anionic phospholipids: Role of arginines at the non-annular lipid binding sites (2019). Biochim Biophys Acta Biomembr. 1861(10):183029. doi: 10.1016/j.bbamem.2019.183029.

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• Renart ML, Giudici AM, Poveda JA, Fedorov A, Berberan-Santos MN, Prieto M, Díaz-García C, González-Ros JM, Counho A. (2019). Conformational plasticity in the KcsA potassium channel pore helix revealed by homo-FRET studies. Sci Rep. 9(1):6215. doi: 10.1038/s41598-019-42405-5. 

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• Giudici AM, Renart ML, Díaz-García C, Morales A, Poveda JA, González-Ros JM. Accessibility of Caons to the Selecvity Filter of KcsA in the Inacvated State: An Equilibrium Binding Study. (2019) Int J Mol Sci. 20(3):689. doi: 10.3390/ijms20030689.