Dr. Iván Quesada Moll
Department: Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE)
Phone: +34 965 222 003
Email:
Website: http://diabetes.umh.es/
Researcher ID: P-6541-2014
Current Position: Professor (Catedrático de Universidad), Universidad Miguel Hernandez.
Research Fields
We study the mechanisms that regulate the function of pancreatic alpha and beta-cells. We also investigate the alterations, adaptations and/or failure of these cells in pathologic conditions such as diabetes and obesity.
Representative Publications
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Soriano S, Castellano‐Muñoz M, Rafacho A, Alonso‐Magdalena P, Marroquí L, Ruiz‐Pino A, Bru‐Tarí E, Merino B, Irles E, Bello‐Pérez M, Iborra P, Villar‐Pazos S, Vettorazzi JF, Montanya E, Luque RM, Nadal Á, Quesada I. Cortistatin regulates glucose‐induced electrical activity and insulin secretion in mouse pancreatic beta‐cells. (2019) Molecular and Cellular Endocrinology. 479:123‐132.
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Merino B, Alonso-Magdalena P, Lluesma M, Ñeco P, Gonzalez A, Marroquí L, García-Arévalo M, Nadal A, Quesada I. Pancreatic alpha-cells from female mice undergo morphofunctional changes during compensatory adaptations of the endocrine pancreas to diet-induced obesity. (2015) Scientific Reports. 5:11622.
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Vieira E, Burris TP, Quesada I. Clock genes, pancreatic function and diabetes. (2014) Trends in Molecular Medicine. 20:685-693.
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Rafacho A, Gonçalves-Neto LM, Santos-Silva JC, Alonso-Magdalena P, Merino B, Taboga SR, Carneiro EM, Boschero AC, Nadal A, Quesada I. Pancreatic alpha-cell dysfunction contributes to the disruption of glucose homeostasis and compensatory insulin hypersecretion in glucocorticoid-treated rats. (2014) PLoS One. 9: e93531.
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Gonzalez A, Merino B, Marroqui L, Ñeco P, Alonso-Magdalena P, Vieira E, Caballero-Garrido E, Soriano S, Gomis R, Nadal A, Quesada I. Insulin hypersecretion in islets from diet-induced hyperinsulinemic female obese mice is associated to several functional adaptations in individual beta-cells. (2013) Endocrinology. 154:3515-3524.