Dr. Francisco Javier Gómez Pérez

Department: Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE) / Biothermodynamics of molecular recognition processes group.

Phone: +34 966 658 467

Email: jgomez@umh.es

Current Position: Associate Professor of Physical Chemistry, Universidad Miguel Hernández.

Research Fields

  • Structural thermodynamical description of molecular recognition processes.

  • Thermodynamics of protein folding.

  • Development of strategies to prevent protein aggregation

Representative Publications

  • M. Romero-Beviar; S. Martínez-Rodríguez.; J. Prieto.; E. Goormaghtigh; U. Ariz; M.L. Martínez-Chantar; J. Gómez and J.L. Neira. The N-terminal domain of the enzyme I is a monomeric well-folded protein with a low conformational stability and residual structure in the unfolded state. (2010)  PEDS: Protein Engineering, Design and Selection 49, 1577–1589.

  • J.L. Neira and J. Gómez. Thermodynamic analysis of the conformational stability of the Streptomyces coelicolor histidine-phosphocarrier protein: characterization of cold denaturation and urea-protein. (2004) European Journal of Biochemistry 271, 2165–2181.

  • M.J. Todd & J. GómezEnzyme kinetics determined using calorimetry: A General Assay for Enzymatic Activity? (2001) Analytical Biochemistry 296, 187–197.

  • J. Gómez & E. Freire. Thermodynamic Mapping of the Inhibitor Binding Site of the Aspartic Protease Endothiapepsin. (1995) Journal of Molecular Biology 252, 337–350.

  • J. Gómez; V.J. Hilser; D. Xie and E. Freire. The Heat Capacity of Proteins. (1995) Proteins: Structure, Function and Genetics 22, 404–412.