Dr. Eugenio Vilanova Gisbert

Department: Instituto de Bioingeniería

Phone: +34 966 658 817

Email: evilanova@umh.es

Current Position: Professor of Toxicology, Universidad Miguel Hernández.

Research Fields

  • Evaluation of toxicity and safety of chemicals and products of biotechnology.

  • Neurotoxicty and identification of esterases target of toxicity and involved in biotransformation of organophosphorus compounds.

  • In vitro models of embryotoxicity based in genomic and proteomic biomarkers of cell differentiation.

Representative Publications

  • Mangas I, Taylor P, Vilanova E, Estévez J, Franca T, Radić Z. Resolving pathways of interaction of mipafox and a sarin-analogue with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches. (2015) Archive of Toxicology.

  • Sogorb MA, Pamies D, de Lapuente J, Estevan C, Estévez J, Vilanova E. An integrated approach for detecting embryotoxicity and developmental toxicity of environmental contaminants using in vitro alternative methods. (2014) Toxicology Letters 230(2): 356-367. Doi: http://dx.doi.org/10.1016/j.toxlet.2014.01.037.

  • Pamies D, Sogorb MA, Fabbri M, Gribaldo L, Collotta A, Scelfo B, Vilanova E, Harris G, Bal-Price A. Genomic and Phenotypic Alterations of the Neuronal-Like Cells Derived from Human Embryonal Carcinoma Stem Cells (NT2) Caused by Exposure to Organophosphorus Compounds Paraoxon and Mipafox. (2014) International Journal of Molecular Sciences 15(1):905-926. doi: http://dx.doi.org/10.3390/ijms15010905.

  • Estevez, Jorge; Mangas, Iris; Angel Sogorb, Miguel Angel; Vilanova, Eugenio. Interactions of neuropathy inducers and potentiators/promoters with soluble esterases. (2013) Chemico-Biological Interactions 203: 245-250 DOI: http://dx.doi.org/10.1016/j.cbi.2012.11.007.

  • Pamies D, Vilanova E, Sogorb MA. Functional pathways altered after silencing Pnpla6 (the codifying gene of Neuropathy Target Esterase) in mouse embryonic stem cells under differentiation. (2013) In Vitro Cellular & Developmental Biology – Animal (2014) 50:261–273.

Patents

Vilanova E and Sogorb MA. Métodos y composiciones para la identificación de compuestos embriotóxicos. (Methods and compositions for identification of embryotoxic chemicals). Oficina Española de Patentes y Marcas, number: ES2363398B1.​

Company Agreements

Contract and agreements of collaborations with public and private organizations for the evaluation of safety of chemicals.

Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche

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Av/ de la Universidad, s/n

03202 Elche, Alicante

Localización

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